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Yaa Asantewaa Osei

Pharmaceutics

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About

Yaa Asantewaa Osei, Ph.D. is a registered Pharmacist and a lecturer at the Department of Pharmaceutics at the Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. She is an early career scientist who is highly motivated to pursue an academic and translational research career. She believes in research that translates into an impact on the lives of people. She has a broad background in Pharmacy with Pharmaceutics as the major and with specific training and expertise in formulation and drug delivery systems development.  She specializes in formulation development (conventional and advanced), excipient development, and pharmacovigilance (post-market surveillance activities). Her desire to see a lot of research uptake has led to the finding of alternative cheaper locally sourced raw materials for their pharmaceutical industries. Through her excipient development projects, the documentation of the effectiveness of local gums and starches as pharmaceutical excipients has been successful. These studies emphasized the possibility of sourcing local pharmaceutical excipients and their great performance in different pharmaceutical industrial usages. More of such projects are ongoing as collaborative work with Crop Research Institute. She also specializes in advanced drug delivery systems formulation with her focus on nanoparticulate drug delivery. Her research in that area has attempted to encapsulate insulin in glucose-responsive polymeric nanoparticles for the management of diabetes. The developed particles showed potential, but more work needs to be done. Collectively, these results and more of such work done have the capacity to fundamentally change the way insulin is delivered to patients and that can improve their quality of life. She is currently exploring the potential of various locally sourced solid lipids as advanced drug delivery vehicles for solid lipid nanoparticulate drug delivery. In addition, she has successfully collaborated with other colleagues, researchers, and facilities and produced peer-reviewed publications. Dr. Osei has extensive experience with formulation design and development and she currently heads the production unit of the Faculty of Pharmacy and Pharmaceutical Sciences at her University In addition, she also focuses on mentoring young females, focusing on helping them to develop an interest in science and especially research.

Research Summary

(inferred from publications by AI)

The researcher's work is a comprehensive exploration of food chemistry and its applications, with a strong emphasis on the properties of polysaccharides, the physicochemical behavior of plant-based foods, and advancements in pharmaceutical quality assessment. They investigate key areas such as the role of plants in food composition, the impact of herbal ingredients on metabolic processes, and the development of innovative drug delivery systems. Their research extends to understanding microbial populations in plant products, the role of food additives in health interventions, and the creation of analytical methods for evaluating drug components in pharmaceutical formulations. This work integrates plant biology, pharmacology, and biotechnology to contribute to the development of sustainable solutions for chronic diseases like diabetes and anaphylaxis.

Research Themes

All Papers

Evaluation of the Disintegrant Properties of Native Starches of Five New Cassava Varieties in Paracetamol Tablet Formulations(2017)
Pharmaceutical Assessment of Watermelon Rind Pectin as a Suspending Agent in Oral Liquid Dosage Forms(2022)
Quality Assessment of Some Essential Children’s Medicines Sold in Licensed Outlets in Ashanti Region, Ghana(2018)
Physicochemical Equivalence and Quality Assessment of Various Brands of Gastro-Resistant Omeprazole Capsules in the Kumasi Metropolis(2022)
Quality characteristics and HPLC detection of phosphodiesterase inhibitors in some herbal capsules indicated for male sexual disorders in Ghana(2024)
Physicochemical characterisation of Piptadeniastrum africana (Hook. F.) gum, a potential pharmaceutical excipient(2021)
Physicochemical and Microbiological Characteristics of Stem Bark Exudate Gum of Cordia millenii Tree in Conventional Release Tablets(2023)
Evaluation of the Physicochemical and Micromeritic Properties of Exudate Gum of Cussonia arborea Stem Bark in Conventional Tablet Formulation(2024)
Cross-Linked Dependency of Boronic Acid-Conjugated Chitosan Nanoparticles by Diols for Sustained Insulin Release(2016)
Pharmaceutical Assessment of Melia azedarach Gum as a Binder and Disintegrant in Immediate-Release Tablets(2022)
Physicochemical and Emulsifying Properties of <i>Melia azedarach</i> Gum(2024)
Development of the RP-HPLC Method for Simultaneous Determination and Quantification of Artemether and Lumefantrine in Fixed-Dose Combination Pharmaceutical Dosage Forms(2024)
Evaluation of the microbial quality of commercial liquid herbal preparations on the Ghanaian market(2023)
Detection, quantification, and investigation of the red blood cell partitioning of cryptolepine hydrochloride(2018)
Cutaneous and systemic anti-allergic potential of xylopic acid in rodents(2021)
Recent Trends in Applications of Nano-Drug Delivery Systems(2021)
Assessment of the physico-chemical and microbial quality of selected extemporaneous paediatric oral formulations frequently prepared at Komfo Anokye Teaching Hospital in Kumasi(2020)
The Effect of the Method of Extraction on the Physicochemical Properties of Allanblackia Floribunda Butter as a Potential Pharmaceutical Excipient(2022)
The Impact of the Extraction Method on Allanblackia floribunda Butter’s Physicochemical Properties as a Possible Pharmaceutical Excipient(2023)
Assessment of the Physicochemical and Emulsifying Properties of Melia Azedarach Gum(2024)
Development of cashew-alginate microbeads and powdered dose forms: prospects for oral vaccine delivery in chickens(2024)

Collaboration Network

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.