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Otchere Addai-Mensah

Medical Diagnostics

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About

Prof. Dr. Dr. Otchere Addai-Mensah is an Associate Professor of Haematology, Immunology and Global Health in the Department of Medical Diagnostics, and the Vice-Dean of Students at the Kwame Nkrumah University of Science and Technology. He is a trained medical doctor and holds a BSc in Human Biology and an MBChB (General Medicine) from the School of Medical Sciences of the KNUST. He also holds an MSc. in Biomedical Sciences from the University of Westminster in London-UK, and a PhD. in Immunology and Biotechnology from the prestigious RWTH University in Aachen, Germany. He has undertaken courses in Pharmacovigilance and Pharmacoepidemiology from the University of Bordeaux in France, and completed the taught component of an MBA in Strategic management.He previously worked as a Researcher at the Fraunhofer Institute for Molecular Biology and Applied Ecology in Germany, and as a Resident in the Departments of Internal Medicine and Pathology at the Komfo Anokye Teaching Hospital in Kumasi.He is a member of the board of the Nursing and Midwifery Council Ghana, the National Vice President of the University Teachers Association (UTAG-KNUST and Ghana), a member of both the British Society of Immunology and the Ghana Medical Association (GMA).He has in the past held both local and national positions like National Spokesperson of the Junior Doctors Association, Secretary of the Ghana Medical Association (Ashanti Division), member of the National Executive Council of the Ghana Medical Association, and a member of the Ashanti Region Prisons Council.Prof. Dr. Dr. Addai-Mensah has extensive experience in scientific research and general management, and has a number of publications in reputable journals to his credit. His research interests are in Infectious Diseases, Malariology, Biomedical Sciences, Immuno-epidemiology, Haematology, Immunology, Transfusion Medicine and Public Health.

Research Summary

(inferred from publications by AI)

The field of health sciences is deeply engaged in addressing various critical areas that impact societal well-being. A primary focus within this domain is health inequalities and interventions, where efforts are made to improve access and outcomes for marginalized communities. Highlighting themes such as Malaria Research, Sexual Function and Dysfunction Studies, HIV Research and Treatment, Hepatitis B Virus Studies, Diabetes, Cardiovascular Risks, Lipoproteins, Monoclonal and Polyclonal Antibodies Research, Pregnancy and Preeclampsia studies, and others, demonstrates a comprehensive approach to understanding and addressing diverse health challenges. These studies often involve innovative methodologies, such as reference intervals, biomarkers, and clinical laboratory practices, aimed at enhancing healthcare quality and outcomes. By integrating insights from infectious diseases, nutritional disorders, cardiovascular issues, and other areas, the research contributes toward creating more equitable healthcare systems that prioritize health and well-being for all individuals.

Research Themes

All Papers

A multicenter study of the prevalence and risk factors of malaria and anemia among pregnant women at first antenatal care visit in Ghana(2020)
Differential expression pattern of co-inhibitory molecules on CD4+ T cells in uncomplicated versus complicated malaria(2018)
Plasmodium falciparum histidine-rich protein 2 diversity in Ghana(2020)
Cytotoxic T Cell-Derived Granzyme B Is Increased in Severe Plasmodium Falciparum Malaria(2019)
Characterization of a novel inhibitory human monoclonal antibody directed against Plasmodium falciparum Apical Membrane Antigen 1(2016)
High-Sensitivity C-Reactive Protein: A Potential Ancillary Biomarker for Malaria Diagnosis and Morbidity(2019)
Assessment of platelet indices and platelet activation markers in children with Plasmodium falciparum malaria(2020)
Acute Phase Responses Vary Between Children of HbAS and HbAA Genotypes During Plasmodium falciparum Infection(2021)
Author Correction: Differential expression pattern of co-inhibitory molecules on CD4+ T cells in uncomplicated versus complicated malaria(2018)
Acquired immune responses to three malaria vaccine candidates and their relationship to invasion inhibition in two populations naturally exposed to malaria(2016)
Malaria and Anaemia: Prevalence, Risk Factors and Impact of Preventive Methods among Pregnant Women in the Akatsi South District, Ghana: A Hospital-Based Cross-Sectional Study(2021)
Plasmodium falciparum histidine-rich protein 2 (PfHRP2) diversity in Ghana(2020)
Effects of Buffer Substitution on Rapid Diagnostic Tests for Malaria Diagnosis(2022)
Incidence of sexual dysfunction: a prospective survey in Ghanaian females(2010)
Prevalence of male sexual dysfunction among Ghanaian populace: myth or reality?(2010)
Prevalence of anaemia and immunological markers among ghanaian HAART-naïve HIV-patients and those on HAART.(2011)
Regular Antenatal Attendance and Education Influence the Uptake of Intermittent Preventive Treatment of Malaria in Pregnancy: A Cross-Sectional Study at the University Hospital, Kumasi, Ghana(2018)
Prevalence and Risk Factors of Preterm Birth Among Pregnant Women Admitted at the Labor Ward of the Komfo Anokye Teaching Hospital, Ghana(2022)
Plant-Based Production of Recombinant Plasmodium Surface Protein Pf38 and Evaluation of its Potential as a Vaccine Candidate(2013)
Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10(2015)
Hepatitis B and C infections in HIV-1 and non-HIV infected pregnant women in the Brong-Ahafo Region, Ghana(2019)
Predominant Complications of Type 2 Diabetes in Kumasi: A 4-Year Retrospective Cross-Sectional Study at a Teaching Hospital in Ghana(2019)
Prevalence of Cardiometabolic Syndrome and its Association With Body Shape Index and A Body Roundness Index Among Type 2 Diabetes Mellitus Patients: A Hospital-Based Cross-Sectional Study in a Ghanaian Population(2022)
Effect of poor glycaemic control on plasma levels and activity of protein C, protein S, and antithrombin III in type 2 diabetes mellitus(2019)
Population-derived cut-off for HbA1c could enhance the identification of metabolic syndrome among non-diabetic population(2020)
Quality of glycemic control in type 2 diabetes mellitus (T2DM) and its association with markers of coagulation and inhibitors of fibrinolysis: A case–control study in the Upper West Region, Ghana(2023)
Reference intervals for selected haematological and biochemical parameters among apparently healthy adults in different eco-geographical zones in Ghana(2021)
Determination of Haematological Reference Ranges in Healthy Adults in Three Regions in Ghana(2019)
Lipid profile, cardiorespiratory function and quality of life of postmenopausal women improves with aerobic exercise(2017)
Prevalence and risk factors of malaria and anaemia and the impact of preventive methods among pregnant women: A case study at the Akatsi South District in Ghana(2022)
Antierythropoietin Antibody Production Is Not Associated with Malaria and Malaria-Related Anaemia in Humans(2019)
Effect of Pulmonary Tuberculosis on Protein C, S, and Antithrombin-III among Therapy-naïve Ghanaian Adults; A Comparative Cross-Sectional Study(2020)
Plasminogen Activator Inhibitor-1 in poorly controlled vs well controlled Type-2 Diabetes Mellitus patients: A case-control study in a district hospital in Ghana(2021)
Renal insufficiency in Ghanaian HIV infected patients: need for dose adjustment(2013)
Isolation and light chain shuffling of a Plasmodium falciparum AMA1-specific human monoclonal antibody with growth inhibitory activity(2021)
Establishment of a phage display platform for the isolation of plasmodium falciparum specific monoclonal antibodies(2015)
Coagulation Factors and Natural Anticoagulants as Surrogate Markers of Preeclampsia and Its Subtypes: A Case–Control Study in a Ghanaian Population(2023)
Early gestational profiling of oxidative stress and angiogenic growth mediators as predictive, preventive and personalised (3P) medical approach to identify suboptimal health pregnant mothers likely to develop preeclampsia(2021)
Placental lesions and differential expression of pro-and anti-angiogenic growth mediators and oxidative DNA damage marker in placentae of Ghanaian suboptimal and optimal health status pregnant women who later developed preeclampsia(2022)
Association between micronutrients, oxidative stress biomarkers and angiogenic growth mediators in early and late-onset preeclamptic Ghanaian women(2023)
Leucocyte Differential Count and Pregnancy Induced Hypertension: Implication for Risk and Disease Assessment(2020)
Biomarkers of oxidative stress and its nexus with haemoglobin variants and adverse foeto-maternal outcome among women with preeclampsia in a Ghanaian population: A multi-centre prospective study(2023)
Novel prognostic Potential of Early Second Trimester and Mid-pregnancy 8-hydroxy-2-deoxyguanosine/Placental growth factor ratio for preeclampsia: A Longitudinal Nested-Case Control Study(2022)
Seroprevalence and Risk Factors for Human Immunodeficiency Virus, Hepatitis B and C Vi-ruses Infections among Blood Donors at the Bolgatanga Regional Hospital in Bolgatanga, Ghana(2010)
Diagnosis of bacterial meningitis in Ghana: Polymerase chain reaction versus latex agglutination methods(2019)
Expression of platelet parameters and platelet membrane glycoproteins in childhood Burkitt lymphoma(2019)
SARS-CoV-2 updates in a West African population and precautionary measures for sustaining quality antenatal care delivery(2020)
Effect of pulmonary tuberculosis on natural anticoagulant activity in therapy-naïve Ghanaian adults; a case-control study(2022)
Safety of Family Replacement Donors vs. Voluntary Non-Remunerated Donors in Komfo Anokye Teaching Hospital, Ghana: A Comparative Study(2015)
Reference Intervals of Prothrombin Time and Activated Partial Thromboplastin Time and Their Association with Age among Healthy Adults in Kumasi, Ghana(2018)
Comediation of Erythrocyte Haemolysis by Erythrocyte-Derived Microparticles and Complement during Malaria Infection(2020)
Differences in Haematological and Biochemical Parameters of Athletes and Non-Athletes(2017)
Interplay between foetal haemoglobin, micronutrients and oxidative stress biomarkers in sickle cell anaemia children(2022)
Anaemia during pregnancy: a cross-sectional study of antenatal attendants at the Madina Pentecost Hospital, La Nkwantanang Municipality, Ghana(2024)
Molecular Characterization of Glucose-6-Phosphate Dehydrogenase: Do Single Nucleotide Polymorphisms Affect Hematological Parameters in HIV-Positive Patients?(2020)
Molecular characterization of Glucose-6-Phosphate Dehydrogenase: do single nucleotide polymorphisms affect hematological parameters in HIV positive patients?(2020)
Coagulation abnormalities in childhood acute lymphoblastic leukemia: assessing the impact of L-asparaginase therapy in Ghana(2021)
Haematological Profile in Pre-Surgery Hernia Patients: A Case-Control Study in Ghana(2022)
Patterns of hernia, haematological profile, and predictive ability of blood cell indices in pre-surgery patients; A case-control study in a district hospital in Ghana(2022)
Plasma levels of fibrinolytic and coagulation biomarkers in HIV‐infected individuals on highly active antiretroviral therapy: A case‐control study in a Northern Ghanaian population(2023)
Adequate Exercise Improves Inflammatory, Gonadal Markers and Sexual Function in Type 2 Diabetics(2018)
Fetal Rhesus D Genotyping and Sex Determination from Maternal Plasma of Rhesus D-Negative Antenatal Population: The Usefulness of Conventional Polymerase Chain Reaction in Resource-limited Settings(2020)
Effect of Pulmonary tuberculosis on natural anticoagulant activity in therapy-naive Ghanaian adults; a case-control study.(2020)
Diagnostic value of neutrophil gelatinase-associated lipocalin and neutrophil-to-lymphocyte ratio in type 2 diabetes mellitus individuals with reduced estimated glomerular filtration rate(eGFR): A case-control study in a municipal hospital in Ghana(2024)
Serum Anti‐Erythropoietin Autoantibodies and Their Association With Younger Age in Paediatric Malaria Cases(2025)

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.