Michael Ofoe Adinku

Surgery

About

Michael Adinku is a team player with good organizations and leadership skills having gained enormous experience working with all shades and categories of people while serving as a Medical Officer, interacting with the under privileged in rural areas and the better endowed in Urban Centres.Trained as general surgeon, Michael has interest in visceral surgery, managing mass casualties and training medical students in managing severely injured patients.He believes that there is a day of accountability for every action or inaction undertaken by man.

Research Summary

(inferred from publications by AI)

The researcher has focused on integrating diverse aspects of cancer biology, including molecular genetics, epigenetics, therapeutic treatments, and population-specific challenges. Their work spans themes such as triple-negative breast cancer through patient-derived tumors, BRCA mutations in genetic risk assessment, epigenetic modifications influencing gene expression, the role of DNA methylation in signaling pathways, and treatment outcomes in diverse populations like Europeans, Africans, and Europeans affected by oesophageal issues. Key findings emphasize the importance of combining genomics with molecular pathways to predict tumor progression and evaluate therapeutic efficacy across these themes, aiming for comprehensive approaches that address genetic mutations, epigenetic changes, and therapeutic interventions in patient-specific contexts.

Research Themes

All (43 Papers)

Life Sciences (31 Papers)

Health Sciences (12 Papers)

All Papers

African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent(2022)

African-Ancestry Associated Gene Expression Signatures and Pathways in Triple Negative Breast Cancer, a Comparison across Women of African Descent(2022)

Kinome focused CRISPR-Cas9 screens in African ancestry patient-derived breast cancer organoids identifies essential kinases and synergy of EGFR and FGFR1 inhibition(2023)

Kinome focused CRISPR-Cas9 screens in African ancestry patient-derived breast cancer organoids identify essential kinases and synergy of EGFR and FGFR1 inhibition(2024)

Data from African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent(2023)

Supplementary Data from African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent(2023)

Supplementary Figure from African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent(2023)

Supplementary Table from African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent(2023)

Data from African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent(2023)

Supplementary Data from African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent(2023)

Supplementary Table from African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent(2023)

Table S5 from Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition(2025)

Table S7 from Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition(2025)

Table S6 from Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition(2025)

Table S2 from Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition(2025)

Table S3 from Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition(2025)

Table S1 from Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition(2025)

Table S4 from Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition(2025)

Data from Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition(2025)

Supplementary Figures from Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition(2025)

Hereditary Susceptibility for Triple Negative Breast Cancer Associated With Western Sub-Saharan African Ancestry(2019)

Investigation of Triple-Negative Breast Cancer Risk Alleles in An International African-Enriched Cohort(2020)

Investigation of triple-negative breast cancer risk alleles in an International African-enriched cohort(2021)

Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment(2024)

Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition(2025)

Comparative analysis of breast cancer characteristics in young premenopausal and postmenopausal women in Ghana(2024)

Acute Gastric Necrosis in a Teenager(2020)

Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment(2023)

Schwannoma extending from the umbilical region to the mid-thigh, compressing the major vessels of the right leg: A case report and review of the literature(2016)

Enhancing Colonoscopy Services in Ghana: A Comprehensive Assessment of Referral Indications and Endoscopic Findings in a Leading Tertiary Care Hospital(2025)

Treating Tropical Pyomyositis (Myositis Tropicans) Using Primary Closure and Vacuum Drainage(2014)

Abstract PO-141: The role of African Duffy-null allele related inflammation on the tumor microenvironment(2022)

Two Cases of Gastroduodenal Perforation Following Cesarean Section(2019)

A Gist of an Obscure Neoplasm in Ghana: Gastrointestinal stromal tumours(2023)

A gist on an obscure neoplasm in Ghana: gastrointestinal stromal tumours(2023)

Abstract C088: DARC/ACKR1 expression modulates immune regulation and influences tumor progression in triple-negative breast cancer(2024)

Evaluating the efficacy of dilute povidone-iodine versus normal saline for preventing surgical site infections following appendectomy: a prospective observational study in Ghanaian tertiary hospital(2025)

Oncologic Anthropology and the African Diaspora: Twenty-Year Anniversary Report, International Center for the Study of Breast Cancer Subtypes (ICSBCS)(2025)

Collaboration Network

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Research Collaboration Map

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.