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Bismarck Dinko

Clinical Microbiology

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Research Summary

(inferred from publications by AI)

The researcher has conducted extensive research on malaria detection, diagnosis, treatment, and control in Ghana. Their work focuses on identifying Plasmodium species after asymptomatic infections using various methods, characterizing their gene expression patterns within host cells, and developing diagnostic tools to prevent malaria in children less than five years old. The findings highlight the effectiveness of treatments like ACT (Asymptomatic Gibbs Reproductive Infection) in detecting specific malaria parasites and suggest that immune evasion mechanisms, such as cross-stage antigenic targeting, can be harnessed for potential antimalarial drug development. Additionally, the researcher has examined seasonal patterns of malaria, including its prevalence in communities with prolonged transmission periods, emphasizing the importance of early diagnostic testing to prevent severe cases among vulnerable populations.

Research Themes

All Papers

Persistent detection of Plasmodium falciparum, P. malariae, P. ovale curtisi and P. ovale wallikeri after ACT treatment of asymptomatic Ghanaian school-children(2013)
Expression of a type B RIFIN in Plasmodium falciparum merozoites and gametes(2012)
Inactivation of <i><scp>P</scp>lasmodium falciparum</i> in whole blood by riboflavin plus irradiation(2013)
Plasmodium falciparum histidine-rich protein 2 diversity in Ghana(2020)
Antibody responses to surface antigens of <i>Plasmodium falciparum</i> gametocyte‐infected erythrocytes and their relation to gametocytaemia(2016)
Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria(2019)
Immune Responses to the Sexual Stages of Plasmodium falciparum Parasites(2019)
Comparison of malaria diagnostic methods in four hospitals in the Volta region of Ghana(2016)
Immune evasion by &amp;lt;i&amp;gt;Plasmodium falciparum&amp;lt;/i&amp;gt; parasites: converting a host protection mechanism for the parasite′s benefit(2016)
Targeting the Plasmodium falciparum proteome and organelles for potential antimalarial drug candidates(2022)
Plasmodium falciparum malaria cases detected for prompt treatment by rapid diagnostic tests in the Ho Teaching Hospital of the Volta Region of Ghana(2018)
Gametocyte Development and Carriage in Ghanaian Individuals with Uncomplicated Plasmodium falciparum Malaria(2018)
The global transcriptome of <i>Plasmodium falciparum</i> mid-stage gametocytes (stages II–IV) appears largely conserved and gametocyte-specific gene expression patterns vary in clinical isolates(2023)
Seasonal Prevalence of Malaria, Fever, Anaemia and Factors Associated with Malaria Prevalence among Children Less than Five in an Area with Prolonged Malaria Transmission in Ghana(2017)
Parasite clearance dynamics in children hospitalised with severe malaria in the Ho Teaching Hospital, Volta Region, Ghana(2022)
Prevalence of Plasmodium falciparum gametocytaemia in asymptomatic school children before and after treatment with dihydroartemisinin-piperaquine (DP)(2023)
Generation of Plasmodium falciparum Gametocytes In Vitro with Specific Considerations for Field Isolates(2022)
Recognition of Plasmodium falciparum gametocyte surface antigens by plasma antibodies in asymptomatic Ghanaian school children(2012)
Inactivation of Plasmodium falciparum in whole body by riboflavin plus irradiation(2014)
ANTIBODY RESPONSES TO SURFACE ANTIGENS OF <i>PLASMODIUM FALCIPARUM</i> GAMETOCYTE-INFECTED ERYTHROCYTES AND THEIR RELATION TO GAMETOCYTAEMIA(2017)
Molecular and immunological characterization of selected Plasmodium falciparum gametocyte-specific genes(2019)
Plasmodium falciparum histidine-rich protein 2 (PfHRP2) diversity in Ghana(2020)
The temporal dynamics of Plasmodium species infection after artemisinin-based combination therapy (ACT) among asymptomatic children in the Hohoe municipality, Ghana(2023)
Two quantitative multiplex assays for the detection of P. falciparum asexual rings and male/female gametocyte developmental stages from human tissues(2024)
&lt;em&gt;Plasmodium falciparum&lt;/em&gt; Subtilisin-Like Domain Containing Protein ((PfSDP) PF3D7_1105800), a Cross-Stage Antigen, Elicits Short-Lived Antibody Response Following Natural Infection with &lt;em&gt;Plasmodium falciparum&lt;/em&gt;(2025)
Plasmodium falciparum Subtilisin-like Domain-Containing Protein (PfSDP), a Cross-Stage Antigen, Elicits Short-Lived Antibody Response Following Natural Infection with Plasmodium falciparum(2025)

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.