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Anthony Afum-Adjei Awuah

Molecular Medicine

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About

Dr. Anthony Afum-Adjei Awuah is a Faculty Member at the Department of Molecular Medicine, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology (KNUST), where he also serves as the Postgraduate Coordinator. He is the Deputy Research Group Leader of the Global Health and Infectious Disease Research Group at the Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR). Additionally, he is the Lead Scientific Officer of the African Research Network for Neglected Tropical Diseases (ARNTD), an affiliate of the Africa Academy of Arts and Sciences, and a member of the Africa Coalition for Epidemic Research, Response, and Training (ALERRT). With extensive experience in clinical research, pandemic preparedness, outbreak response, and community-based studies in resource-limited settings, Dr. Afum-Adjei Awuah has been instrumental in the design, planning, and implementation of multiple outbreak response research initiatives across Ghana and Africa. His work includes leading seroprevalence studies on WHO-priority pathogens and contributing to the evidence base for public health interventions in the region. Beyond outbreak response, he is actively involved in clinical trials, including drug and vaccine studies, ensuring the rigorous implementation of research protocols in challenging environments. A former WHO/TDR Clinical Research and Development Fellow, Dr. Afum-Adjei Awuah currently serves on the steering committee of the WHO/TDR Africa Regional Training Centre, supporting capacity-building efforts for clinical research in the region. Passionate about research training and mentorship, he co-convenes the Skills for Excellence in Science Series (SEXISS), which delivers specialized training programs using advanced pedagogical approaches, problem-based learning, and group-based methodologies. Through this initiative and his role as Postgraduate Coordinator, he plays a key role in strengthening the next generation of biomedical and health researchers in Africa. Dr. Afum-Adjei Awuah’s career reflects a commitment to conducting high-quality research in the trenches of resource-limited settings while fostering collaborations that translate scientific findings into tangible public health impact. His work continues to shape the landscape of infectious disease research, particularly in the areas of pandemic preparedness and outbreak response research in Africa.

Research Summary

(inferred from publications by AI)

The researcher conducts a comprehensive study focusing on immune cell function and interactions across various domains, particularly examining cytokine signaling pathways, T-cell responses, and mechanisms of immune detection in different health contexts. Their work integrates insights into TB research, COVID-19 epidemiology, immunology, microbiome studies, liver disease, metabolic diseases, and systemic inflammation to understand the interplay between immune response, microbial composition, and infectious pathogen interactions.

Research Themes

All Papers

Constitutive STAT3 phosphorylation and IL-6/IL-10 co-expression are associated with impaired T-cell function in tuberculosis patients(2018)
A scorecard of progress towards measles elimination in 15 west African countries, 2001–19: a retrospective, multicountry analysis of national immunisation coverage and surveillance data(2021)
Editorial: Vaccines and immunization services during the pandemic era and beyond(2024)
A conceptual approach to the rationale for SARS-CoV-2 vaccine allocation prioritisation(2021)
Vaccines and Immunization Services During the Pandemic Era and Beyond(2024)
Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis(2017)
Dynamics of T-cell IFN-γ and miR-29a expression during active pulmonary tuberculosis(2014)
An IL7RA exon 5 polymorphism is associated with impaired IL-7Rα splicing and protection against tuberculosis in Ghana(2018)
Epidemiological profile of SARS-CoV-2 among selected regions in Ghana: A cross-sectional retrospective study(2020)
High seroprevalence of SARS-CoV-2 in Burkina-Faso, Ghana and Madagascar in 2021: a population-based study(2022)
Seroprevalence of SARS-CoV-2 in urban settings in three sub-Saharan African countries (SeroCoV): a study protocol for a household-based cross-sectional prevalence study using two-stage cluster sampling(2021)
Malaria and other infections induce polyreactive antibodies that impact SARS‐CoV‐2 seropositivity estimations in endemic settings(2024)
Malaria and other infections induce polyreactive antibodies that impact SARS-CoV-2 seropositivity estimations in endemic settings(2024)
Mutations in ace2 gene modulate cytokine levels and alter immune responses in Mycobacterium tuberculosis and SARS-CoV-2 co-infection: a Cameroonian cohort(2025)
Genetic association of ACE2 rs2285666 (C>T) and rs2106809 (A>G) and susceptibility to SARS-CoV-2 infection among the Ghanaian population(2025)
Determinants of long-term SARS-CoV-2 immune responses in asymptomatic-to- moderate COVID-19 patients in sub-Saharan Africa(2025)
Postoperative Morbidity and Mortality of Perforated Peptic Ulcer: Retrospective Cohort Study of Risk Factors among Black Africans in Côte d’Ivoire(2016)
Variations in levels of IL-6 and TNF-α in type 2 diabetes mellitus between rural and urban Ashanti Region of Ghana(2015)
Alternative Quantiferon cytokines for diagnosis of children with active tuberculosis and HIV co-infection in Ghana(2017)
The role of candidate miRNAs in T Cell response during acute pulmonary tuberculosis in Kumasi, Ghana(2014)
Prevalence and risk factors of obesity among undergraduate student population in Ghana: an evaluation study of body composition indices(2024)
Prevalence and Risk Factors of Obesity among Undergraduate Student Population in Ghana: An Evaluation Study of Body Composition Indices(2023)
Systemic inflammatory response syndrome and model for end-stage liver disease score accurately predict the in-hospital mortality of black African patients with decompensated cirrhosis at initial hospitalization: a retrospective cohort study(2018)
Sero-prevalence and occupational risk factors for Brucella infection among slaughterhouse workers and butchers in Kumasi, Ghana(2016)
Missed opportunities for the diagnosis of Brucella infection among slaughterhouse workers at the Kumasi Abattoir, Ghana(2017)
Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms(2024)
Human<i>ace2</i>and<i>tmprss2</i>polymorphisms for predicting susceptibility to tuberculosis and COVID-19 co-infection in Cameroonian cohort(2024)
A simulation-based method to inform serosurvey designs for estimating dengue force of infection using existing blood samples(2023)
A simulation-based method to inform serosurvey design for estimating the force of infection using existing blood samples(2023)
(Sero)Prevalence of (Re)Emerging Major Arbovirus Infections in Africa: A Systematic Review and Meta-Analysis Protocol(2024)
Seroprevalence of dengue in the Democratic Republic of Congo, Ghana and Senegal: results of the SERODEN study(2025)
Innovative methodological approach to assess dengue transmission: findings from the SERODEN study in Africa(2025)
Investigating the potential of clinical variables and <i>ace2</i>/<i>tmprss2</i> genetic variants as a biomarkers for COVID-19 and malaria co-infection in Cameroon(2025)
Differential risk of cardiovascular complications in patients with adult type-2 diabetes mellitus in Ghana using clustering analysis: A hospital-based cross-sectional study(2024)
Differential risk of cardiovascular complications in patients with type-2 diabetes mellitus in Ghana: A hospital-based cross-sectional study(2025)
Population-based cross-sectional seroprevalence study of SARS-CoV-2 infection in urban residential areas in Ghana(2025)

Collaboration Network

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.