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Amma Aboagyewa Larbi

Biochemistry and Biotechnology

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About

Dr Amma Larbi  holds a PhD in Immunology, an MSc in Clinical Microbiology and BSc in Biochemistry from KNUST. She conducted her Masters and PhD research at Noguchi memorial Institute for medical (NMIMR), University of Ghana, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, MA, USA and Weill Cornell Medical School, Department of Infectious Diseases, NY, USA. She is a member of professional bodies such as Ghana Science Association, Ghana Immunological society, Organization for Women in Science for the developing world, BioStruct-Africa, International Society for Infectious diseases, and American Society of microbiology. Her research interests span broadly on host-pathogen interactions, immunology of infectious diseases, Neglected tropical diseases (NTDs) and Genomics. Her current research  is focused on the role of microbiome in NTDs as well as malaria genomics.

Research Summary

(inferred from publications by AI)

The researcher's research agenda centers on several key areas: the study of antibiotic resistance mechanisms within bacterial systems, the role of the gut microbiota in health and disease, the development of immune response dynamics, advancements in antibody production, investigations into the COVID-19 pathogenesis, investigation of parasitic diseases, studies on insect symbiosis with bacteria, exploration of malarial pathology, examination of global health issues such as preeclampsia and childhood cancers, and contributions to vaccine development through immunoinformatics approaches. These themes collectively aim to advance understanding in bacterial resistance, immune system regulation, and public health solutions across diverse human health challenges.

Research Themes

All Papers

High prevalence of antibiotic resistance in commensal Escherichia coli from healthy human sources in community settings(2021)
The microbiota vault initiative: safeguarding Earth’s microbial heritage for future generations(2025)
Dosage of X‐linked Toll‐like receptor 8 determines gender differences in the development of systemic lupus erythematosus(2014)
Dosage of X-linked Toll-like receptor 8 determines gender differences in the development of systemic lupus erythematosus (BA4P.216)(2014)
Production of IgG autoantibody requires expression of activation‐induced deaminase in early‐developing B cells in a mouse model of SLE(2014)
Molecular characterization of interactions between the D614G variant of SARS-CoV-2 S-protein and neutralizing antibodies: A computational approach(2021)
Impact of the SARS-CoV-2 S-protein G476S mutation on the interaction with human ACE-2 receptor and neutralizing antibodies(2021)
Impact of the SARS-CoV-2 S-protein G476S mutation on the interaction with human ACE-2 receptor and neutralizing antibodies(2021)
Iron stores in steady‐state sickle cell disease children accessing care at a sickle cell disease clinic in Kumasi, Ghana: A cross‐sectional study(2022)
Antibiotic resistance and <i>mec</i>A characterization of <i>Staphylococcus hominis</i> from filarial lymphedema patients in the Ahanta West District, Ghana: A cross‐sectional study(2023)
The role of nuclear factor kappa B (NF-κB) in filarial pathology(2021)
Poor Nutritional Status Among Human Filarial Lymphedema Patients in Ghana: A Cross-Sectional Study(2021)
Antibiotic resistance profile and genomic characterization of Staphylococcus aureus isolates from filarial lymphedema patients in Ghana(2025)
In silico drug repurposing for filarial infection predicts nilotinib and paritaprevir as potential inhibitors of the Wolbachia 5′-aminolevulinic acid synthase(2021)
Foeto-maternal complications associated with low birth weight: A prospective multicenter study in northern Ghana(2022)
Assessing knowledge of sickle cell disease and health beliefs on premarital genetic screening among healthcare trainees at a tertiary institution: A cross‐sectional study(2023)
<i>Plasmodium falciparum</i> coinfection is associated with improved IgE and IgG3 response against hookworm antigens(2022)
Blood collection tubes impact expression of activated CD4+ and CD8+ T cells in human whole blood assay(2023)
Transcriptomic profiling identifies host-derived biomarker panels for assessing cerebral malaria(2022)
Evaluation of endothelial biomarkers in the pathogenesis of cerebral malaria in Ghanaian children(2020)
Malaria Elimination: The Role and Value of Sero-Surveillance(2021)
Spatial and Temporal Distribution of Pediatric Cancers in Southern Ghana: A Retrospective Observational Study(2025)
Immunoinformatics‐Based Multi‐Epitope Vaccine Design Against <i>P. falciparum‐</i> Causing Malaria: A Computational Approach(2025)

Collaboration Network

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.