Alexander Kwarteng

Biochemistry and Biotechnology

About

Dr. Alexander Kwarteng holds an MPhil in Clinical Microbiology (KNUST, Kumasi) and PhD in Molecular Biomedicine (University of Bonn, Germany). He did his post-doctoral studies at the Kumasi Centre for Collaborative Research into Tropical Medicine (KCCR). Dr. Kwarteng is a faculty member at the Biochemistry and Biotechnology Department of Kwame Nkrumah University of Science and Technology and has extensive experience in immunobiology, genomics, and transcriptomics of infectious diseases as well as has been involved in several filed clinical trials in infectious diseases. His ongoing projects are focused in areas of helminths, tuberculosis, and meningitis.

Research Summary

(inferred from publications by AI)

The researcher has conducted extensive research across multiple disciplines, focusing on advancements in immunology, virology, parasitology, and public health. Their work encompasses a broad range of topics including the study of parasitic diseases, investigation of viral resistance mechanisms, exploration of immunological responses to specific pathogens, and development of strategies for disease prevention and treatment. The researcher has published numerous papers on these themes, utilizing innovative methods such as immunological diagnostics, genetic engineering approaches, and nutritional studies to address challenges in public health and disease management. Their research highlights the importance of integrating immunological insights with virological dynamics to improve disease control efforts and fosters interdisciplinary collaboration across various scientific domains.

Research Themes

All Papers

Doxycycline Improves Filarial Lymphedema Independent of Active Filarial Infection: A Randomized Controlled Trial(2012)

Doxycycline Leads to Sterility and Enhanced Killing of FemaleOnchocerca volvulusWorms in an Area With Persistent Microfilaridermia After Repeated Ivermectin Treatment: A Randomized, Placebo-Controlled, Double-Blind Trial(2015)

Hyperreactive Onchocerciasis is Characterized by a Combination of Th17-Th2 Immune Responses and Reduced Regulatory T Cells(2015)

Elevated Adaptive Immune Responses Are Associated with Latent Infections of Wuchereria bancrofti(2012)

Wuchereria bancrofti-infected individuals harbor distinct IL-10-producing regulatory B and T cell subsets which are affected by anti-filarial treatment(2019)

Killing filarial nematode parasites: role of treatment options and host immune response(2016)

Influence of seasonal variation on reported filarial attacks among people living with lymphedema in Ghana(2019)

Immunoepidemiological Profiling of Onchocerciasis Patients Reveals Associations with Microfilaria Loads and Ivermectin Intake on Both Individual and Community Levels(2014)

Immunity in Filarial Infections: Lessons from Animal Models and Human Studies(2017)

Financial burden impact quality of life among lymphatic Filariasis patients(2021)

Multi-drug resistant bacteria isolates from lymphatic filariasis patients in the Ahanta West District, Ghana(2022)

Shift in the skin microbiome among individuals presenting with filarial lymphedema compared to non-filarial healthy individuals in Ghana(2022)

Spatial variation in lymphatic filariasis risk factors of hotspot zones in Ghana(2021)

Highlighting the Relevance of CD8+ T Cells in Filarial Infections(2021)

Antibiotic resistance and mecA characterization of Staphylococcus hominis from filarial lymphedema patients in the Ahanta West District, Ghana: A cross‐sectional study(2023)

Knowledge and perceptions of lymphatic filariasis patients in selected hotspot endemic communities in southern Ghana(2023)

The role of ultrasonography in the differentiation of the various types of filaricele due to bancroftian filariasis(2010)

The role of nuclear factor kappa B (NF-κB) in filarial pathology(2021)

Genome editing as control tool for filarial infections(2021)

Bacterial diversity significantly reduces toward the late stages among filarial lymphedema patients in the Ahanta West District of Ghana: A cross‐sectional study(2022)

The filarial and the antibiotics: Single or combination therapy using antibiotics for filariasis(2022)

Mapping Spatial Variation and Impact of the National MDA Program on Lymphatic Filariasis Elimination in Ghana: An Initial Study(2022)

Computational insight into biofilm inhibitory activity of Ketidocillinone B and C against Pseudomonas aeruginosa: A way to combat Antibiotic Resistance among Filarial Lymphedema Patients(2025)

Use of medicinal plants as a remedy against lymphatic filariasis: Current status and future prospect(2023)

Financial burden impact quality of life among Lymphatic Filariasis Patients(2020)

Eosinophil: An innate immune cell with anti‐filarial vaccine and biomarker potential(2023)

Mass Drug Administration Interruption by COVID-19 reportedly increases lymphatic filarial attacks, pains, and perceived increased lymphatic filarial infection transmission in rural Ghana(2021)

The Potentials and Pitfalls of Microarrays in Neglected Tropical Diseases: A Focus on Human Filarial Infections(2016)

Financial burden impact quality of life among Lymphatic Filariasis Patients(2021)

Lack of dermal residing MF does not alter filarial-specific antibody profiles.(2015)

Transcriptomics and Immune Profiles of Asymptomatic Filarial-Infected Individuals(2015)

Financial Burden Reportedly Impact Quality of Life Among Lymphatic Filariasis Pathology Patients in Ghana(2020)

Poor Nutritional Status Among Human Filarial Lymphedema Patients in Ghana: A Cross-Sectional Study(2021)

Spatial Variation in Risk Factors of Lymphatic Filariasis in Hotspot Zones in Ghana(2020)

Multi-drug Resistant (MDR) bacteria isolates from Lymphatic Filariasis (LF) patients in the Ahanta West District, Ghana(2022)

Financial burden reportedly impact quality of life among Lymphatic Filariasis Pathology Patients in Ghana(2020)

Correction: Multi-drug resistant bacteria isolates from lymphatic filariasis patients in the Ahanta West District, Ghana(2022)

Phytochemical intervention for lymphatic filariasis and filarial lymphedema(2023)

Nutritional predictors of lymphatic filariasis progression: Insights from a machine learning approach(2025)

Computational Insight into Biofilm Inhibitory Activity of Ketidocillinone B and C against Pseudomonas aeruginosa: A Computational Study(2025)

Integrating geospatial tools is crucial for enhancing control strategies against human lymphatic filarial infections in Ghana: A comprehensive review(2025)

High Prevalence of Hepatitis B Virus Infection in the Age Range of 20-39 Years Old Individuals in Lome(2017)

Seroprevalence of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus among volunteer blood donors in the National Blood Transfusion Center of Lome(2017)

The therapeutic landscape of HIV-1 via genome editing(2017)

Targeting the SARS-CoV2 nucleocapsid protein for potential therapeutics using immuno-informatics and structure-based drug discovery techniques(2020)

Exploring Onchocerca volvulus Cysteine Protease Inhibitor for Multi-epitope Subunit Vaccine Against Onchocerciasis: An Immunoinformatics Approach(2021)

Computational Mutagenesis and Inhibition of Staphylococcus aureus AgrA LytTR Domain Using Phenazine Scaffolds: Insight From a Biophysical Study(2024)

Disrupting quorum sensing by exploring conformational dynamics and active site flexibility of LasR protein in Pseudomonas aeruginosa(2025)

Phenazine Scaffolds as a Potential Allosteric Inhibitor of LasR Protein in Pseudomonas aeruginosa(2025)

The burden of drug resistance tuberculosis in Ghana; results of the First National Survey(2021)

Determinants and Variations of COVID-19 Vaccine Uptake and Responses Among Minority Ethnic Groups in Amsterdam, the Netherlands(2022)

Current meningitis outbreak in Ghana: Historical perspectives and the importance of diagnostics(2017)

Oropharyngeal carriage of potential meningitis-causing bacteria in a Ghanaian prison(2023)

Vitamin D Deficiency Is Common in Ghana despite Abundance of Sunlight: A Multicentre Comparative Cross-Sectional Study(2021)

Molecular characterization of interactions between the D614G variant of SARS-CoV-2 S-protein and neutralizing antibodies: A computational approach(2021)

Transmission of SARS-CoV-2 in northern Ghana: insights from whole-genome sequencing(2021)

Transmission of SARS-CoV-2 in Northern Ghana; Insights from Whole Genome Sequencing(2020)

Impact of the SARS-CoV-2 S-protein G476S mutation on the interaction with human ACE-2 receptor and neutralizing antibodies(2021)

Computational analyses of the G476S variant of SARS-CoV-2: A focus on the interaction with human ACE-2 and neutralizing antibodies(2020)

Impact of the SARS-CoV-2 S-protein G476S mutation on the interaction with human ACE-2 receptor and neutralizing antibodies(2021)

Profiling immuno-metabolic mediators of vitamin B12 deficiency among metformin-treated type 2 diabetic patients in Ghana(2021)

Profiling Immuno-Metabolic Mediators of Vitamin B12 Deficiency Among Metformin-Treated Type II Diabetes Patients in Ghana(2020)

Prevalence of Methicillin-Resistant Staphylococcus Species Among Filarial Lymphedema Patients in Ahanta West District of Ghana(2021)

Profiling vitamin D, its mediators and proinflammatory cytokines in rheumatoid arthritis: A case–control study(2022)

Iron stores in steady‐state sickle cell disease children accessing care at a sickle cell disease clinic in Kumasi, Ghana: A cross‐sectional study(2022)

Malaria Parasitaemia in Apparently Healthy Individuals and its Relationship to Serum Ferritin in a Malaria-Endemic Area: A Cross-Sectional Study(2024)

In silico drug repurposing for filarial infection predicts nilotinib and paritaprevir as potential inhibitors of the Wolbachia 5′-aminolevulinic acid synthase(2021)

Wolbachia Ferrochelatase as a potential drug target against filarial infections(2023)

Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa(2021)

Cell-free DNA as a complementary diagnostic tool for neglected tropical diseases towards achieving the WHO NTDs elimination by 2030(2024)

Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa(2020)

Abstract PO-093: Circulating tumor DNA (ctDNA) from peripheral blood is detectable among Ghanaian breast cancer patients(2020)

Abstract 81: Studying Ghanian Cancer Genomes Using Cell-free DNA(2021)

Gut Microbiome-Targeted Nutrition Interventions and Growth among Children in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis(2024)

Assessing knowledge of sickle cell disease and health beliefs on premarital genetic screening among healthcare trainees at a tertiary institution: A cross‐sectional study(2023)

Hemolysis scavenger proteins and renal function marker in children with sickle cell disease at steady state: A cross‐sectional study(2023)

Physical inactivity and barriers to physical activity among Type-2 diabetics in Kumasi, Ghana(2023)

Examining Research Positionality – Understanding Self as a First Step to Transnational Research(2023)

Burden of respiratory viral infections among inmates of a Ghanaian prison(2019)

Prevalence and risk factors of hypertension among public servants in Ejisu-Juaben municipality, Ghana(2023)

Comparison of Modified Manual Acid-Phenol Chloroform Method and Commercial RNA Extraction Kits for Resource Limited Laboratories(2023)

Prospects of Immunology Education and Research in Developing Countries(2021)

Use of social media in a national Tuberculosis Drug Resistance Survey: lessons from the first anti-tuberculosis drug resistance survey in Ghana(2019)

Nutritional and health status of people living with HIV/AIDS in the eastern region of Ghana(2019)

Solid waste motor tricycle operators in Kumasi, Ghana, harbour respiratory pathogens; a public health threat(2023)

Key drivers of graduate students’ interest in the subject of immunology in a tertiary institution of Ghana(2018)

Graduate students’ interest in immunology as a discipline(2017)

Assessing the variability and the role of inflammatory cytokines and monocyte chemoattractant protein-1 (MCP-1) in predicting stroke among hypertensives: A case-control study(2022)

Cardiovascular risk assessment of people living in prison in the Northern region of Ghana(2024)

Blood collection tubes impact expression of activated CD4+ and CD8+ T cells in human whole blood assay(2023)

Transcriptomic profiling identifies host-derived biomarker panels for assessing cerebral malaria(2022)

An Assessment of the Integrated Malaria Control Programme in the Obuasi Municipality(2008)

Financial burden impact quality of life among Filarial Pathology Patients(2020)

Comparison of Complete Campylobacter fetus Genomes Derived from Public Repositories(2023)

Genomic Insights into the Diversity, Antimicrobial Resistance, and Zoonotic Potential of Campylobacter fetus Across Diverse Hosts and Geographies(2025)

Antimicrobial Activity of Chromolaena Odorata and Syzygium Aromaticum Against Multi-Drug Resistant Clinical Isolates from Diabetic Foot Ulcer Patients: A Cross-Sectional Study(2025)

Antimicrobial Activity of Chromolaena Odorata and Syzygium Aromaticum against multi-drug resistant clinical isolates from diabetic foot ulcer patients: A cross-sectional study(2025)

Spatial and Temporal Distribution of Pediatric Cancers in Southern Ghana: A Retrospective Observational Study(2025)

Collaboration Network

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Research Collaboration Map

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.