Albert Dompreh

Medical Diagnostics

About

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Research Summary

(inferred from publications by AI)

The researcher has conducted extensive research across multiple themes within health sciences, focusing on infectious diseases, parasitic infections, immunological studies, pharmacokinetics and treatments for diseases such as TB, HIV/AIDS, and HIV-related complications. Key findings include a strong emphasis on the prevalence of parasitic infections like Helicobacter pylori and HIV-1 RNA loads in Ghanaian individuals, as well as the effectiveness of antituberculosis drugs in reducing viral load markers. The researcher has also explored molecular mechanisms underlying disease transmission, such as retroviral loads in HIV patients and bacterial colonization with Toxoplasma gondii. Additionally, they have investigated therapeutic interventions like efavirenz and Nevirapine for reducing HIV suppression outcomes in adolescents. Their work underscores the importance of understanding immune responses and viral dynamics to develop more effective treatments.

Research Themes

All (49 Papers)

Health Sciences (39 Papers)

Life Sciences (10 Papers)

All Papers

Helicobacter pylori Infection Is Associated with Higher CD4 T Cell Counts and Lower HIV-1 Viral Loads in ART-Naïve HIV-Positive Patients in Ghana(2015)

Helicobacter pyloriCoinfection Is Associated With Decreased Markers of Immune Activation in ART-Naive HIV-Positive and in HIV-Negative Individuals in Ghana(2015)

Pharmacokinetics of First-Line Antituberculosis Drugs Using WHO Revised Dosage in Children With Tuberculosis With and Without HIV Coinfection(2015)

Pharmacokinetics of the First-Line Antituberculosis Drugs in Ghanaian Children with Tuberculosis with or without HIV Coinfection(2016)

Evaluation of the Adequacy of WHO Revised Dosages of the First-Line Antituberculosis Drugs in Children with Tuberculosis Using Population Pharmacokinetic Modeling and Simulations(2018)

Evaluation of the Adequacy of the 2010 Revised World Health Organization Recommended Dosages of the First-line Antituberculosis Drugs for Children(2017)

Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana(2019)

The Clinical Features and Immunological Signature of Cyclospora cayetanensis Co-Infection among People Living with HIV in Ghana(2022)

High Clinical Burden of Cryptosporidium spp. in Adult Patients with Acquired Immunodeficiency in Ghana(2024)

Correction: Lower prevalence of Blastocystis sp. infections in HIV positive compared to HIV negative adults in Ghana(2019)

Association of Molecular Detections of Microsporidia in Stool Samples with Clinical and Immunological Parameters in Ghanaian HIV Patients(2024)

Epidemiological, Clinical, and Immunological Features of Ghanaian People-Living-with-HIV (Human Immunodeficiency Virus) and Molecular Proof of Cystoisospora belli in Their Stool Samples(2025)

Effect of Genetic Variation of NAT2 on Isoniazid and SLCO1B1 and CES2 on Rifampin Pharmacokinetics in Ghanaian Children with Tuberculosis(2017)

Effect of malnutrition on the pharmacokinetics of anti-TB drugs in Ghanaian children(2021)

Prevalence and the evaluation of culture, wet mount, and ELISA methods for the diagnosis of Trichomonas vaginalis infection among Ghanaian women using urine and vaginal specimens(2019)

Profiling of cardio‐metabolic risk factors and medication utilisation among Type II diabetes patients in Ghana: a prospective cohort study(2017)

Sero-prevalence of Hepatitis B and C viral co-infections among HIV-1 infected ART-naïve individuals in Kumasi, Ghana(2019)

Antibody Detection and Kinetics of Antibody Production during Early Stages of Immunization with Hepatitis B Virus Vaccine(2007)

immunization with Hepatitis B virus vaccine(2007)

Replicative co-infections with human immunodeficiency virus 1 and 2 as well as hepatitis B and C virus in Ghanaian individuals(2024)

Maternal‐Fetal Transmission of Human Parvovirus B19 Genotype 3(2006)

Pattern and predictors of immunologic recovery in HIV infected patients(2015)

The immunological response of HIV-positive patients initiating HAART at the Komfo Anokye Teaching Hospital, Kumasi, Ghana.(2013)

Vertical transmission of HIV in Ghanaian women diagnosed in cord blood and post‐natal samples(2005)

Policy adherence and clinical effect of early infant diagnosis of HIV exposed children: impact on Elimination of mother to child transmission (EMTCT(2022)

Tenofovir diphosphate concentrations in dried blood spots predict future HIV suppression but not virologic failure in adolescents with HIV(2025)

Population pharmacokinetics of efavirenz in HIV and TB/HIV coinfected children: the significance of genotype-guided dosing(2019)

Effect of Rifampin-Isoniazid-Containing Antituberculosis Therapy on Efavirenz Pharmacokinetics in HIV-Infected Children 3 to 14 Years Old(2018)

Pharmacogenetic predictors of nevirapine pharmacokinetics in Ghanaian children living with HIV with or without TB coinfection(2021)

Effect of First-Line Antituberculosis Therapy on Nevirapine Pharmacokinetics in Children Younger than Three Years Old(2019)

Pharmacokinetics of Tenofovir Diphosphate, Lamivudine Triphosphate and Emtricitabine Triphosphate in Adolescents With HIV Infection With and Without Tuberculosis Coinfection(2025)

Pharmacokinetics and pharmacodynamics of adult dolutegravir tablets in treatment-experienced children with HIV weighing at least 20 kg(2023)

Molecular Characterization and Clinical Description of Non-Polio Enteroviruses Detected in Stool Samples from HIV-Positive and HIV-Negative Adults in Ghana(2020)

Demographic, Clinical Profile of Rheumatoid Arthritis Patients and Their Association with Disease Severity in Ghana(2024)

GB virus C and HIV-1 RNA load in single virus and co-infected West African individuals(2006)

GB virus C genotype 1 is rarely transmitted vertically but acquired during infancy in West Africa(2006)

Levels of pro-inflammatory biomarkers among HIV patients on highly active antiretroviral therapy (HAART) and HAART naive patients(2018)

Correlation of Haematological Parameters with TNF-α and Interleukin (IL-6) in Seropositive HIV Patients on Highly Active Antiretroviral Therapy (HAART) and HAART Naïve Patients(2018)

Levels of pro-inflammatory biomarkers among HIV patients on highly active antiretroviral therapy (HAART) and HAART naive patients(2018)

Intestinal Colonization with Tropheryma whipplei—Clinical and Immunological Implications for HIV Positive Adults in Ghana(2021)

Screening for Schistosoma spp. and Leishmania spp. DNA in Serum of Ghanaian Patients with Acquired Immunodeficiency(2022)

Epidemiological, clinical and immunological features of Schistosoma spp., Stronglyoides stercoralis and Taenia spp. infections in Ghanaian HIV patients(2025)

Ear, nose and throat lesions in hiv/aids patients in komfo anokye teaching hospital, kumasi, ghana.(2012)

Very low prevalence of Mansonella perstans-specific cell-free DNA in serum samples of Ghanaian HIV patients(2023)

Seroprevalence of Toxoplasma gondii Infection among Pregnant Women in the Ashanti Region of Ghana(2016)

A Comparative Study Between Nasopharyngeal/Oropharyngeal, Faecal and Saliva Viral Shedding In Ghanaian COVID-19 Patients attending Komfo Anokye Teaching Hospital (KATH), Kumasi from October – December, 2020(2021)

Comparative epidemiology of Ghanaian individuals with molecular proof of Entamoeba histolytica with and without concomitant human immunodeficiency virus infection(2025)

Evaluation of Each Three Entamoeba histolytica- and Strongyloides stercoralis-Specific Real-Time PCR Assays Applying Test Comparisons Without Reference Standards(2025)

Associations of HIV status and the abundance of blaCTX-M and vanB resistance genes in stool samples of Ghanaian individuals(2025)

Collaboration Network

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Research Collaboration Map

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About This Profile

This profile is generated from publicly available publication metadata and is intended for research discovery purposes. Themes, summaries, and trajectories are inferred computationally and may not capture the full scope of the lecturer's work. For authoritative information, please refer to the official KNUST profile.